This study was done to investigate a possibility of an epidemia in Gölkarşı village of Edremit county of Van, on establishing 5 brucellosis cases in a family of 12 persons dealing with stock-breeding who gave the information that some other patients with similar complaints were present in the village. In this purpose, we went the cited village and made physical examination and serological research on the village’s people who had complaints such as fever, sweating and joint ache. 98 blood samples obtained from individuals who had complaints compatible with brucellosis were first evaluated by lam agglutination method and those giving positive results were seperated. 9 serum samples out of 12 which were positive with lam agglutination gave positivity at titers changing between 1/160 and 1/2560. 3 serum samples at titer lower than 1/160 with tube agglutination were reexamined with Coombs test, the rest 9 samples were reexamined with tube agglutination test with rivanol to clarify the course of diseaase. It was established that the animals belonged to the families in which the brucellosis cases existed were diseased and abortus cases were frequent. In our region, because of the common tradition of fresh cheese consumption obtained by fermenting milk without pasteurisation; it was considered that infection source was the diseased animals and contamination route was both direct contact and consumption of fresh cheese and butter prepared from infected milk of those animals.

Acute appendicitis may caused morbidity and mortality because of high perforation ratio especially at the early childhood and elderly patients. At this study we retrospectively evaluated 84 patients who were operated at the pediatric surgery clinic and 176 patients who were operated at the General Surgery Clinic. Perforation rate was found as 50 % in patients younger than 15 years age and 41.5 % in patients older than 16 years age. There was no statistically significant difference between the perforation rates of the groups. Perforation rate was 86 % in 0-4 years age group and 83 % in patients older than 60 years age group. Complications like ileus, intra-abdominal abscess and sepsis were found significiantly higher in pediatric group. Mortality rate was higher in pediatric group (2.7 %) compare to adult group (0.77 %). Hospital stay time was significantly longer in 0-4 years age and older than 60 years age groups compare to the other groups.

In this study we aimed to examine 85 strains of Enterobacter obtained from various clinical materials sent to Microbiology and Clinical Microbiology laboratory Yüzüncü Yıl University Faculty of Medicine in two years periods retrospectively because of the importance of infections Enterobacteriaceae have recently increased. 38 strains 38(%44.7) of 85 Enterobacter strains were grown materials sent from pediatric clinic, 11 (12.9 %) from Urology clinic, 7 (8.2 %) from Orthopedic Clinic, 6 (7.2 %) Chest Diseases Clinic, 5 (5.9 %) from Ear Throat Nose Clinic, 5 (5.9 %) from General Surgery, 5 (5.9 %) from Internal Medicine clinic, 4 (4.7 %) from Gynecology and Obstetrics clinic, 3 (3.5 %)Physical Therapy and Rehabilitation Clinic and 1 (1.2 %) from Pediatrics Surgery Clinic or outpatients clinics. Fifty five strains (64.7 %) belonged to E.cloacae, 14 strains (16.5 %) to E.aerogenes, 11 (12.9 %) to E. asburiae and it was established that the isolation sites were most frequently respiratory and urinary sistems, then wound, blood, ear and intraabdominal materials and rarely cerebrospinal fluid, eye and vaginal secretions. Examination of antimicrobial susceptibility revealed that the most strains were resistant to ampicillin and most of the cephalosporins and generally susceptible to amikacin, imipenem, norfloxacin and ciprofloxacin.

In our study the effects of 14 antibiotics on 66 Salmonella serotypes isolated from various clinical specimens were examined. The bacteria were isolated by culturing the stool, urine, blood, pus and CSF samples on suitable media, were typed by comparison first with polyvalent Salmonella antisera and thereafter with monovalent Salmonella antisera. Fiftysix (84.9%) of 66 Salmonella serotypes were isolated from stool, 4 (6.1%) from urine, 3 (4.5%) from blood, 2 (3.0%) from pus and 1(1.5%) from CSF. The distribution of the serotypes were as follows ; 36 (54.5%) S. paratyphi B, 17 (25.8%) S. paratyphi A, 9 (13.6%) S. typhimurium and 4 (6.1%) S. arizona. An antibiotic susceptibility test with microdilution technique was performed to search the effects of 14 antibiotics on bacteria. Two (3%) Salmonella serotypes were resistant to ciprofloxacin, 5 (7.6%) were resistant to chloramphenicole and ceftazidime, 8 (12.1%) were resistant to imipenem and 10%-33.3% of Salmonella serotypes were found to be resistant to other antibiotics.

Parvovirus B19 (PVB19) is known as the causative agent of erythema infectiosum which is often seen in the chidhood. It has also been reported to cause arthropathy in adults, transient aplastic crisis in the patients with chronic haemolytic anemia and chronic anemia in the patient with AIDS. This study was aimed to investigate whether PVB19 may have some role in the appearance of symptoms in adults. For this, a hundred patients which had no rheumatoid factor (RF) were used as material in this study and PVB19 IgM-ELISA (IBL-Hamburg, Germany) kits were used for analysis. Six percent (6 %) positivity for PVB19 IgM was determined. This result is thought to have some sort of importance in the patients with rheumatoid complains.

Organophosphate poisoning which is frequently seen in rural and agricultural areas of undeveloped and devoloping countries, is an important cause of mortality and morbidity. In this study, 34 cases (23F, 11M) from Van and surrounding provinces with the diagnosis of organophosphate poisoning, who were followed up and treated in the clinic of internal Medicine between 1997-1999 in Yüzüncü Yıl University, Faculty of medicine, were retrospectively evaluated. Poisoning were frequent in female (F %68, M %32) and young population (mean age;F 21years and M 28.9years) and in summer seasons (%38). Most of cases were from rural areas (rural %61.7, center %39.3), and had taken pesticides via gastrointestinal (GİS) route %73 in order to commit suicide %64.7. Cinically muscarinic signs and symptoms (miosis %82.4, bradycardia %64.7, hypersalivation %52.9, abdominal cramp %52.9) were frequently seen. Most prominent nicotinic finding was respiratory depression that required mechanical respiratory support (%20.5). Mean inpatient duration was 6.7 (3-16) days, and the mortality rate was %5.8. At the admission to the hospital, there were leukocytosis in %70, leucopenia in %5.8, increase of ALT and ALT levels in %8.8 of cases, and in the 3 and 4th inpatient days all these parameters eventually became normal. The young age of cases, the goal of commit suicide, poisoning via GİS way and the fruquency in female population were the observations found noticible. As a conclusion, people, especially young and female population live in rural and agricultural areas should be educated about the severity of such poisoning, and the necessity of pesticides must be sold and controlled thereafter by concerning executive units should be pointed out.