E-ISSN: 2587-0351 | ISSN: 1300-2694
Van Medical Journal - Van Med J: 19 (1)
Volume: 19  Issue: 1 - 2021
1. Cover

Pages I - II

KLINIK MAKALE
2. Analysis of Patients who were Admitted to Burn Unit and Operated
Abdulmenap Güzel, Lokman Soyoral, Mehmet Reşit Öncü, Cumhur Çakır
Pages 1 - 7
Aim: To evaluate the burn patients in Van and nearby regions who admitted our burn clinic and underwent surgical intervention, retrospectively. Method: One hundred and four patients who admitted to and were operated at Van Teaching and Research Hospital Burn Unit were evaluated by means of their age, body weight, sex, socioeconomic status, household population, social security, etiology, total surface area and localization of the burn, time elapse between the trauma and the hospital admittance, number of operations, type of anesthesia, the type of surgical interventions performed, the duration of hospitalization, the complications encountered and mortality. Results: There was no statistically significant correlation between the length of stay and demographic data of the patients. Eight hundred twenty patients (451 male 369 female) were hospitalized at our burn clinic; totally 197 operations were performed to 104 patients (57 male 47 female). Fifty percent of those patients underwent at least two operations. General anesthesia was applied to 94.2% of the patients. Children constituted 75% of the patientt population and 46% of the whole patient population was aged between 1-5 years old. Hot water burns were found to be the leading cause of burn injury (40.4%). The etiology of the burns for 26.9% of the operated patients was hot oven burns. The socioeconomic status of 62.5% of the patient population was poor. The burn injuries were most commonly occurred at houses with at least seven inhabitants. 53.8% of the patients were burnt at home and 75% of them admitted to the hospital in the first 24 hours. Wound infections were observed in 40.4% of the operated patients, pneumonia in the 12.5%, bacteremia in the 18.3%. 6.7% of the patients treated in the burn unit were connected to a mechanic ventilator and 2.9% of the operated patients were deceased. Conclusion: The children should be taken care of and not be left alone at home. They should be kept away from fire and resources. The socioeconomic status of the families should be improved. Besides, it was concluded that establishment of modern burn facilities would help to facilitate emergency care of burn patients and decrease the infection rate.

3. Treatment and follow up results of our pediatric patients with acute peritoneal dialysis
Abdullah Ceylan, Serdar Epçaçan, Mehmet Melek, Oğuz Tuncer, Burhan Beger, Mehmet Göksu
Pages 8 - 12
Purpose: The aim of the study is to determine the etiological, clinical, laboratory features and the prognosis of our patients with acute peritoneal dialysis. Material and methods: 10 patients who were indicated for acute peritoneal dialysis were included to study between May 2008 and May 2009. Age, gender, diagnosis, duration of dialysis, prognosis and laboratory findings between and after dialysis were noted for each patient. Patients with previously diagnosed chronic renal insufficiency were excluded from the study. Patients and results: The total number of the patients included to study was 10. Three (30%) of them were girl and 7 (70%) were boy. The range of their age was between 4 days and 8 years. The mean age was 1.87±2.53 years. The main reason for acute peritoneal dialysis was metabolic acidosis and the others were acute renal insufficiency and hyperkalemia. Three (30%) of the patients full recovered, 10 (10%) underwent continuous peritoneal dialysis, 2 (20%) patients underwent hemodialysis. Four (40%) of the patients died. Conclusion: Acute peritoneal dialysis is a good and effective method that can be applicated when necessary.

4. Evaluation of Lung Cancer Cases; Analysis of Three Years
Hülya Günbatar, Bünyamin Sertoğullarından, Bülent Özbay, Aysel Sünnetçioğlu, Selami Ekin
Pages 13 - 20
Aim: In this study we investigated clinical findings and properties of patients diagnosed as lung tumor within last 3 years. Material and Methods: We evaluated retrospectively demographic data, diagnostic methods, treatment modalities, and survival of cases diagnosed as lung cancer in last 3 years. Results: Of patients 108 (77.7%) were male and 31( 22,3%) female. The diagnostic methods were bronchoscopic forceps biopsy in 72.8% patients, transtorasic needle aspiration biopsy 4.9%, trucut biopsy in 3.7%. Of the cases 96.5% were primary lung cancer, 2,8% metastatic, and 0,7 % lymphoma. The histopathologic types were as follows; 30,9% Squamous cell carcinoma, 27,3 % small cell carsinoma, 8,6% adenocarsinoma, 28,1 %,unknown nature, 1 case carcinoid cancer, and 1 case adenoid cystic carcinoma,. Distribution of management protocols of patients was 56,8% chemotherapy (CT), 16% CT and radiotherapy (RT), 11% RT, 4 cases surgery, and 5 cases only symptomatically treated. Mean life durations were found 10 months in squamous cell carsinoma, 11 months in small cell carsinoma, 16 months in adenocarsinoma. According to the stage, mean life durations were found as follows; 11 months in stage IV, 10 months in stage IIIb, 14 months in stage IIb. Conclusion: We concluded that cell type had no effect and the treatment had positive effect on survival of patients with lung cancer,

5. The Relationship Between Catheterisation And Nosocomial Urinary Tract Infections In Our Clinic And Bacterial Prevalance: A Retrospective Study
Cavit Ceylan, Serkan Doğan, Süha Şen, Öner Odabaş
Pages 21 - 26
Aim: We retrospectively evaluated the role of urinary catheterization as an etiologic factor in patients with urinary tract infection (UTI), detected in the past year in our urology clinic. Matherial and Method: Patients treated in urology clinic in one year with positive urine cultures, were included in the study and were evaluated in terms of previous surgery, catheterisation and isolated microorganisms. Results: A total of 131 patients, 35 women (26.7%) and 96 men (73.3%), were aged between 18-83 years (mean: 51.9 years). 121 of them (%92.4) had previous urological surgery while 10 had not (%7.6). Surgical procedures were endoscopic in 80 (66.1%) and open surgery in 41 (33.9%). Urinary catheterisation were performed in 105 of the patients (%80.2) while in 26 (%19.8) were not. Microorganisms isolated in urine cultures were Escherichia coli in 51 (%38.9), Pseudomonas aeroginosa in 26 (%19.8), Klebsiella spp. in 24 (%18.3), Enterococcus faecalis in 11 (%8.4), Acinetobacter baubanni in 5 (%3.8), Stafilococcus aureus in 4 (%3.1), Serratia marcences in 4 (%3.1), Stafilococcus epidermidis in 2 (%1.5), Morganella spp. in 2 (%1.5) and Stenotrophomonas maltophilia in 2 (%1.5), respectively. Conclusion: The most common cause of UTIs diagnosed in our urology clinic in the past year is urinary catheterisation. The most isolated microorganism in urine cultures of patients; with or without previous surgery; is Escherichia Coli (38.9%).

6. The Effect of Postoperative Tramadol Consumtion of Lornoxicam and Paracetamol Used in Preemptive
Öznur Uludağ, Gönül Ölmez Kavak, Orhan Tokgöz, Feyzi Çelik, Adnan Tüfek, Zeynep Baysal Yıldırım, Haktan Karaman, Abuzer Uludağ
Pages 27 - 32
Aim: In this study, postoperative analgesic efficacy of lornoxicam and paracetamol used in preemptive in microsurgery lumbar discectomy were investigated. Method: This study was performed on 63 patients, ASA class I - II group, 18 to 65 years, undergoing micro-lumbar discectomy.The patients were divided into 3 groups randomized after the operating table. Group I (n = 21) to 1 g paracetamol in 100 mL 0.09% NaCl, Group II (n = 21) to 8 mg lornoxicam in 100 mL in 0.09% NaCl and Group III (n = 21) to 100 mL 0.09% NaCl infusion iv was performed 15 min before the operation. Standard endotracheal intubation was performed after induction of anesthesia. After the operation, a postoperative analgesia requirement in all cases was achieved by using the device PCA (bolus dose of 20 mg, locked for 15 minutes, 4 hour limit of 200 mg) with iv tramadol. Following the operation, the same dose of study medication was repeated 8 and 16 hours after the first dose. Result: SAS -VAS scores, tramadol consumption, side effects and patient satisfaction were recorded during 24 hours. The SAS - VAS scores and the consumption of tramadol were similar in Group I and II, but statistically significantly were lower according to Group III. The side effects and patient satisfaction did not different in three groups. Conclusion: The preemptive use of paracetamol and lornoxicam in the treatment of postoperative pain after lumbar disc microsurgery was provided a safe, effective and similar analgesic effect.

OLGU SUNUMU
7. Fludarabine Associated Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia: a Case Report
Cengiz Demir, Murat Atmaca, Mehmet Fatih Özbay, Eyüp Taşdemir, Murat Alay
Pages 33 - 35
Massive tumor lysis is an unusual event that is generally confirmed to histologically aggressive neoplasms and is very rare in chronic lymphocytic leukemia. Risk factors include the type of malignancy, some tumor-related factors such as high numbers of circulating tumor cells and a large tumor burden, the presence of individual factors such as preexisting renal insufficiency, and the type and intensity of anticancer regimen used. Fludarabine is a frequently used purine analogue in the treatment of patients with chronic lymphocytic leukemia. Tumor lysis syndrome with acute renal failure is a very rare complication of fludarabine therapy in patients with chronic lymphocytic leukemia. We report the occurrence of tumor lysis syndrome after the infusion of fludarabine therapy in a patient with chronic lymphocytic leukemia.

8. Poisoning with Henbane in 32 Weeks Pregnant
Sevdegül Karadaş, Ayşe Güler, Musatafa Şahin, Lütfi Behçet
Pages 36 - 38
We aimed to present a case of intoxication occurring as a result of Hyoscyamus niger L ingestion in a pregnant patient under the shed of literature. Twenty three year-old-age, gravida 2, parity 1 pregnant woman in 32nd gestational week was admitted to the emergency room with complaints of nausea, vomiting, blurred vision and meaningless speech all developing after eating a plant that she didn’t know its name and was similar to lettuce. On physical examination, tachycardia, facial flushing and mydriasis were noticed and sinus tachycardia was present on electrocardiogram. Gastric lavage was performed via nasogastric tube, activated charcoal was given and supportive therapy was started. The patient who was monitored under observation was discharged after her symptoms were relieved. In conclusion; in intoxications resulting in anticholinergic syndrome, treatment in pregnant women is the same as in nonpregnant and consists of a good observation, monitorization and supportive approach. Early diagnosis and treatment are lifesaving.

9. A Case of Generalized Darier’s Disease
Necmettin Akdeniz, Serap Güneş Bilgili, Ömer Çalka, İrfan Bayram
Pages 39 - 41
Darier’s disease (Keratosis follicularis, Darier-White disease), is a rare autosomal dominant genodermatosis characterized by greasy hyperkeratotic papules and plaques in seborrheic areas. In this paper, a 32-year-old female patient with Darier’s disease was presented for its rarity and generalized course.

10. Can the fetal nuchal translucency be determined before the eleventh week of the pregnancy when it is routinely measured? A case report, and theories of fetal nuchal translucency
İbrahim Alanbay, Hakan Çoksüer, Cihangir Mutlu Ercan, Aşkın Evren Güler, Emre Karaşahin, Uğur Keskin, Ali Ergün
Pages 42 - 45
First trimester nuchal translucency (NT) is the most effective screening strategy for Down syndrome as well as other aneuploidy and anomalies. Current guidelines for the measurement of nuchal translucency recommend that the measurement should be taken between 11 and 14 weeks’ gestation when the fetal crown–rump length is between 45 and 84 mm. Cardinal proposed mechanisms for the increase in NT thickness include altered composition of the extracellular matrix, abnormalities of the heart and great arteries, and disturbed or delayed lymphatic development. Increased NT measurement in early pregnancy may be associated with distended jugular sacs and suggest a disturbance in lymphangiogenesis as seen in Turner syndrome. Therefore, when excess NT in early gestation weeks(<11 weeks) is observed one should think of Turner Syndrome.

DERLEME
11. Congenital Malaria
A.Barış Akcan, Mediha Kazık
Pages 46 - 50
Congenital malaria is the least known and a very neglected manifestation of malaria. Most of the information is limited to case reports in children born to non-immune women. With the use of molecular techniques, congenital infection is being detected among infants born to women in endemic countries. Also there is a lack of consensus on the clinical guidelines for its management. More research is needed about this subject.

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