Aim: Investigation of the effect of anemia on diastolic echocardiographic parametrs in potients having moderate (Hb 7-10 g/dl) and deep anemia (Hb < 7 g/dl) and comparison of these findings with non-anemic healthy people. Material and Method: 40 patients having iron-deficiency anemia whose Hb parameters are below 7 gr/dl without any other accompanying illness and 40 other moderate iron-deficiency anemic patients (Hb 7-10 g/dl ) are included in the study. As the control group 20 healthy volunteers having similar demographic charesteristics were recruited in the study. At the beginning all subjects were assesed for medical history, cardiac risk factors and general systematic problems after which blood pressure and pulse were determined and a medical examination was performed. Hb and creatinine levels were determined in all patients. An electrocardiographic (ECG) and transthorasic echocardiographic examination were performed on each subject. The cardiac rithym was determined by a 12-derivation ECG. In the echocardiographic examination, beside all conventional parameters, mitral valvular pulse wave (PW) Doppler, mitral annulus PW tissue doppler and mitral valve M-mode propogation velocity examinations were performed. Findings: In the anemic patients compared to the control group, the left atrial diameter and LV end diastolic diameter were significantly greater than the controls. Five patients in the deep and 7 patients in the moderate anemic groups were found to have impaired diastolic filling. Results: Anemia negatively affects the cardiac diastolic functions. According to the severity of anemia, the left atrial diameter and LV end diastolic diameter of the heart increase.

Material-methods: The study was made about urinary incontinence of 216 patients who referred our clinic between August 2008-November 2008. Findings: The mean menoposal age of the cases was 46.6. The urinary incontinence was seen in %45.3. The most seen type was mixed urinary incontinence (%64.3). Advanced age, high parity, not to use hormone replacement therapy was detected as meaningful risk factors. Conclusion: Urinary incontinence is a common problem influencing the social experience of the postmenoposal women.The prevalence was detected %45.3 in our study.The urinary incontinence prevalence of the postmenoposal period was stated % 32-73 in the literature.The quality of the life is augmentable in the postmenoposal women by diagnosing the risk factors of urinary incontinence and spend effort to improve.

Aim: In the last 12 years have been pathological changes of renal biopsy findings in the Van region and in the years of assessment. Methods: All renal biopsy results were evaluated retrospectively in adults between January 2004 and October 2009 at the Yuzuncu Yil University Faculty of Medicine and were compared with January 1997-December 2003 period; also combined all the data were evaluated. Results: In total, 231 biopsies were performed. While first period can not be enough material in 14 patients (10%), the second period 1 (1%), respectively (p, 0.001). Fifteen cases(6.5%) excluded from all patients because of can not be obtained enough material. The most common diagnoses; SLE (20.7%), MPGN (22.1%), proliferative GN (9.7%), amyloidosis (8.3%) and membranous GN (8.3%) respectively. Conclusion: İn our area the most frequent pathologies observed were MPGN(22.7%) and SLE(20.7%), there is no significant change between the periods (1997-2003/2004-2009) in terms of histopathologic diagnoses. Insufficient material for second review period was reduced, histopathologic findings of end stage renal disease second period was higher than first period.

Duodenal atresia is the most common intestinal atresia diagnosed in a fetus. Early planning of the surgical procedures with the help of prenatal diagnosis reduces neonatal mortality and morbidity. We would like to discuss a prenatally diagnosed case together with his postnatal management as an impressive example of this topic. A 24 year-old patient gravida 1, para 0 was admitted to Obstetrics and Gynecology Clinic after membrane rupture and her obstetric ultrasonography revealed a fetal biometry compatible with 34 weeks of gestation together with polyhydramnios and a “double bubble” sign was noticed in abdominal examination of the fetus. Since the fetal heart rates were bradycardic, a cesarean section was performed to the patient and a 1900 g male baby was delivered with 7-9 apgars. The baby was operated by the Department of Pediatric Surgery upon the sign of “double bubble” seen on the direct abdominal graphies which were taken over the prenatal diagnosis of duodenal atresia. The baby in whose operation atretic duodenal ends were anastomised “side to side” was discharged in 16th postoperative day. Ultrasonography is quite helpful in the prenatal diagnosis of duodenal atresia, and prognosis of these patients depends on gestational week at delivery, presence of additional anomalies and delay in diagnosis or not. Delay in diagnosis may lead to death as a result of vomiting, aspiration pneumonia, electrolyte imbalance, dehydratation and gastric perforation and thus, early diagnosis is lifesaving.

Radiation recall dermatitis is characterized by acute inflammatory reaction which is a rare condition seen following the administration of chemotherapeutics or other drugs on a region where radiation therapy is applied previously. A 40-year-old woman with breast carcinoma was applied palliative radiotherapy for the metastatic lesion on L4 vertebra using single posterior field with a dose of 30 Gy in September 2007. The patient used additive and alternative medicine since the time of diagnosis, and was applied Trastuzumab-Docetaxel-Epirubicine chemotherapeutic regimen in February 2008. In August 2008, the patient admitted with the complaints of pain, stiffness, and redness on the skin of the flank region where radiation therapy was applied. Punch biopsy of the affected skin revealed ‘radiodermatitis’. The patient was recovered after topical treatment.

Gastrointestinal stromal tumor is the most common mesenchymal tumor of the gastrointestinal tractus. The main treatment of localized gastrointestinal stromal tumor is surgery. Before the utilization of imatinib, there had been very limited efficacy of conventional chemotherapeutic agents in the treatment of inoperabl and metastatic gastrointestinal stromal tumor. After the approval of imatinib in the treatment of gastrointestinal stromal tumor, a dramatic improvement in the survival of this disease was achieved. However if progression occurs while using imatinib, it will be appropriate to change the treatment into sunitinib. If progression is observed after the second line treatment, then other tyrosine kinase inhibitors like nilotinib or sorafenib can be an option depending on the available data from phase II trials.